The topic of which specific mechanism fevers act by is one of grand discussion which has also been fuelled by many myths and non-scientifically based assertions. This video provides an overview of the most prominent theories of the existence and action of fevers in immunological response. it discusses the processes that the human body undergoes while in a state of fever.

This video was made by Health Science 4DM3 students: Yu Fei
Xia, Zil E-Huma Nasir, Ivelina Velikova and Mohammed Abdul-Khaliq

Copyright McMaster University 2017

References:

Canadian Pharmacists Association – English [Internet]. [cited 2017
Nov 6]. Available from: https://www.pharmacists.ca/

Ontario G of. The flu [Internet]. Ontario.ca. 2014 [cited 2017 Nov
6]. Available from: https://www.ontario.ca/page/flu-facts

Kid Care for Fevers: Myths, Misconceptions and the Facts | St. Louis
Children’s Hospital [Internet]. 2015 [cited 2017 Nov 6]. Available
from: http://www.stlouischildrens.org/articles/kidcare/fever-myths-versus-facts

Cavaillon J-M. Good and bad fever. Critical Care. 2012;16(2):119.

Walter EJ, Hanna-Jumma S, Carraretto M, Forni L. The
pathophysiological basis and consequences of fever. Critical Care.
2016;20(1).

Evans SS, Repasky EA, Fisher DT. Fever and the thermal regulation of
immunity: the immune system feels the heat. Nature Reviews Immunology.
2015 Jun 1;15(6):335-49.

Young P, Saxena M, Bellomo R, Freebairn R, Hammond N, Haren FV, et
al. Acetaminophen for Fever in Critically Ill Patients with Suspected
Infection. New England Journal of Medicine. 2015Mar;373(23):2215–24.

Schmitt BD. Fever phobia: misconceptions of parents about fevers.
American Journal of Diseases of Children. 1980 Feb 1;134(2):176-81.

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How do we stay safe from the growing epidemic of antibiotic resistant bacteria? NIAID is researching ways to keep us safe. MedlinePlus page on antibiotic resistance: http://ow.ly/TzR330ixwM4

Video Outline
0:38 Antimicrobial resistance epidemiology
1:02 Examples of resistant bacteria
1:11 Tuberculosis
1:31 Gonorrhea
1:46 MRSA
2:13 How does antimicrobial resistance occur?
3:25 What can you do to fight antimicrobial resistance?
4:32 Research at NIAID

Accessible version of video at MedlinePlus:
https://medlineplus.gov/medlineplus-videos/antibiotics-vs-bacteria-fighting-the-resistance/

Animation: Jeff Day
Intern: Priscilla Seah
Narration: Jennifer Sun Bell
Music: Da Bakkwo Instrumental, by Jin Yeop Cho, Marc Ferrari, and Matt Hirt via Killer Tracks