In this video Doctor Andrea Furlan explains why is Vitamin B12 so important, and how to diagnose its deficiency. The talks about megaloblastic anemia, pernicious anemia and microcytic anemia. She also talks about the blood tests and normal ranges. She explains how to obtain Vitamin B12 from diet and supplementation, including oral, sublingual and intra-muscular injections.

00:00 Introduction
00:55 Why is Vitamin B12 important
01:12 Normal blood test
01:23 Anemia
02:13 Homocysteine test
02:33 Recommended daily intake
02:54 Dietary sources
03:19 Malabsorption
03:35 Pernicious anemia
04:20 Pain
04:54 Severe deficiency
05:17 Interaction with other medications

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ALERT: This video is not intended to replace medical
advice. If you think you have a condition that is
causing you pain, please consult with your doctor
to get a diagnosis and a treatment plan for you.
The intent of this video is only for educational
purposes.
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Vitamin B12 deficiency can occur in all kinds of individuals. It may be of particular concern if you are following a vegan or vegetarian diet, or taking medications that reduce your absorption ability of vitamins. This video looks at what exactly a vitamin B12 deficiency can lead to and the ways in which you can obtain vitamin B12 through your diet or by taking B12 supplements.

This video was created by Demystifying Medicine students Dhruvika Joshi, Prabhjot Khabra, Minahil Jabeen and Vanessa Lombardo.

Copyright McMaster University 2017

References:

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14. National Heart, Lung, and Blood Institute (2011). What are the signs and symptoms of pernicious anemia? Retrieved from https://www.nhlbi.nih.gov/health/health-topics/topics/prnanmia/signs

15. Niculescu, M., & Zeisel, S. (2002). Diet, Methyl Donors and DNA Methylation: Interactions between Dietary Folate, Methionine and Choline. The Journal of Nutrition,132, 2333-2335.

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18. Vogiatzoglou, A., Smith, A. D., Nurk, E., Berstad, P., Drevon, C. A., Ueland, P. M., … & Refsum, H. (2009). Dietary sources of vitamin B-12 and their association with plasma vitamin B-12 concentrations in the general population: the Hordaland Homocysteine Study. The American journal of clinical nutrition, 89(4), 1078-1087.

19. Whitney, E., Rolfes, S., Hammond, G., & Piche, L. (2011). Understanding Nutrition (1st ed., pp. 332-334). Toronto: Nelson Education Ltd.

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