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Chapters

0:00 Introduction
0:46 Pale or Yellowish Skin
1:02 Fatigue
1:20 Needle-like Sensations
1:38 Difficulty in mobility
1:55 Mouth Ulcers or Glossitis
2:19 Dizziness and Breathlessness
2:34 Disrupted Vision
2:54 Frequent Mood Changes

Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition of low blood and tissue levels of vitamin B12.[4] In mild deficiency, a person may feel tired and have a reduced number of red blood cells (anemia).[1] In moderate deficiency, soreness of the tongue, apthous ulcers, breathlessness, jaundice, hair loss and severe joint pain (arthralgia) and the beginning of neurological symptoms, including abnormal sensations such as pins and needles, numbness and tinnitus may occur.[1] Severe deficiency may include symptoms of reduced heart function as well as more severe neurological symptoms, including changes in reflexes, poor muscle function, memory problems, irritability, ataxia, decreased taste, decrease level of consciousness, depression, anxiety, guilt and psychosis.[1] Infertility may occur.[1][5] In young children, symptoms include poor growth, poor development, and difficulties with movement.[2] Without early treatment, some of the changes may be permanent.[6]

Causes are categorized as decreased absorption of vitamin B12 from the stomach or intestines, deficient intake, or increased requirements.[1] Decreased absorption may be due to atrophic gastritis pernicious anemia, surgical removal of the stomach, chronic inflammation of the pancreas, intestinal parasites, certain medications, and some genetic disorders.[1] Medications that may decrease absorption include proton pump inhibitors, H2-receptor blockers, and metformin.[7] Decreased intake may occur in vegetarians, vegans and the malnourished.[1][8] Increased requirements occur in people with HIV/AIDS, and in those with shortened red blood cell lifespan.[1] Diagnosis is typically based on blood levels of vitamin B12 below 120–180 pmol/L (170 to 250 pg/mL) in adults.[2] Elevated methylmalonic acid levels may also indicate a deficiency.[2] A type of anemia known as megaloblastic anemia is often but not always present.[2] Individuals with low or “marginal” vitamin B12 in the range of 148–221 pmol/L (200–300 pg/mL) may not have classic neurological or hematological signs or symptoms.[2]

Treatment consists of oral or injected vitamin B12 supplementation; initially in high daily doses, followed by less frequent lower doses as the condition improves.[3] If a reversible cause is found, that cause should be corrected if possible.[9] If no reversible cause is found, or when found it cannot be eliminated, lifelong vitamin B12 administration is usually recommended.[10] Vitamin B12 deficiency is preventable with supplements containing the vitamin which is recommended in pregnant vegetarians and vegans, and not harmful in others.[2] Risk of toxicity due to vitamin B12 is low.[2]

Vitamin B12 deficiency in the US and the UK is estimated to occur in about 6 percent of those under the age of 60, and 20 percent of those over the age of 60.[1] In Latin America, about 40 percent are estimated to be affected, and this may be as high as 80 percent in parts of Africa and Asia.[1] Marginal deficiency is much more common and may occur in up to 40% of Western populations.[2]

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This Top 4 Best Supplements for Arthritis, Joint Pain Supplements 2018 is made according to verified amazon customer reviews.
this is not made by any doctor

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1.Schwartz Bioresearch Turmeric Curcumin Capsules
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3.Doctor Recommended Turmeric Curcumin Capsules
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4.Vimerson Health Turmeric Curcumin with Bioperine
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Supplements are not meant to serve as a replacement medicine for those with ailments or diseases. However, it can assist in reducing pain and delivering additional benefits. Turmeric, for instance, can provide many benefits, especially when combined with other herbal ingredients.Turmeric Curcumin with Bioperine supplement can reduce your joint pain easily.

What Is Turmeric and Curcumin?

Turmeric is a spice (some call it a herb) that is part of the ginger family. It comes in two different colors: white and yellow turmeric. There is in fact a black turmeric as well, but is not as well-known. When people refer to turmeric, they mostly mean the yellow version as this is the most common type of turmeric. White turmeric is also quite rare and is typically replaced by ginger.

Native to India and often referred to as “Indian saffron”, yellow turmeric has a brown/yellow skin and orange/yellow flesh. It smells like a mix of ginger and orange with a peppery and bitter flavor.

Turmeric is mostly known in powder form, created by boiling, drying, and grinding the root. Apart from the important role it has played in Indian cuisine, turmeric also known to have strong medicinal properties.
Curcumin

The yellow color is caused by the high concentration of curcumin, the most beneficial compound in turmeric. Curcumin has been used as a traditional herbal medicine for many centuries, particularly in India and China.

The positive effects of turmeric and curcumin on our health have made this spice more popular in western medicine as well. Turmeric and curcumin supplements are on the rise as more people learn about the potential health benefits.

Curcumin has been linked to slowing down the effects of Alzheimer’s disease and reducing chronic pain and inflammation. There have also been results of studies suggesting that curcumin can be effective in treating depression symptoms as it helps to increase the serotonin and dopamine levels (known as “feel good” neurotransmitters) in the brain. Curcumin also helps with faster muscle recovery and decreases joint pain.

Turmeric contains around 3-5% curcumin. So to make the most of this healthy compound, you would need to consume quite a lot of turmeric. This is why people often prefer to use curcumin supplements.

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